Fuel injectors directly affect the air/fuel ratio for the engine and new fuel injectors do require a new or updated tune.
The injectors that we typically support are Ford Performance (Racing), Injector Dynamics, Siemens Deka and Bosch.
With submitting a request including new fuel injectors please include the flow rate in pounds per hour as well as a manufacturers part number. If you do not have this information a link to the product is also helpful.